| Hotkey | Action |
| Ctrl+N | Create new wiki |
| Ctrl+O | Open wiki |
| Ctrl+S | Save wiki |
| Alt+F4 | Exit |
| Ctrl+Z | Undo |
| Ctrl+Y | Redo |
| Ctrl+X | Cut |
| Ctrl+C | Copy |
| Ctrl+V | Paste |
| Ctrl+F8 | Open preferences dialog |
| Ctrl+F | Search in note |
| Ctrl+H | Search and replace in note |
| F3 | Find next |
| Shift + F3 | Find previous |
| Ctrl+Alt+T | Create new note with the same nesting level as current one |
| Ctrl+Shift+T | Create child note |
| Ctrl+Shift+Del | Remove current note |
| F2 | Rename note |
| Ctrl+E | Edit current note properties |
| Ctrl+Shift+F | Find note |
| Ctrl+Alt+A | Attach files |
| Ctrl+Shift+D | Copy title of current note to clipboard |
| Ctrl+Shift+P | Copy path of current note to clipboard |
| Ctrl+Shift+A | Copy attachment's path to clipboard |
| Ctrl+Shift+L | Copy link for current note to clipboard |
| Ctrl+R | Reload wiki |
| Ctrl+D | Add current note to bookmarks / Remove current note from bookmarks |
| F4 | Switch between code and preview tabs |
| Shift+F4 | Switch to HTML code for current wiki note |
| Ctrl+F1 | About OutWiker |
| Ctrl+B | Bold |
| Ctrl+I | Italic |
| Ctrl+Shift+I | Bold italic |
| Ctrl+Shift+I | Monospaced |
| Ctrl+U | Underlined |
| Ctrl+= | Subscript |
| Ctrl++ | Superscript |
| Ctrl+, | Smaller font |
| Ctrl+. | Larger font |
| Ctrl+Alt+L | Align left |
| Ctrl+Alt+C | Align centre |
| Ctrl+Alt+R | Align right |
| Ctrl+Alt+J | Justify |
| Ctrl+1 ... Ctrl+6 | Heading level 1-6 |
| Ctrl+G | Bulleted list |
| Ctrl+J | Numbered list |
| Ctrl+K | Strikethrough |
| Ctrl+M | Insert the <IMG> tag For HTML notes |
| Ctrl+M | Insert thumbnail For wiki notes |
| Ctrl+L | Link |
| Ctrl+Alt+N | Anchor |
| Ctrl+Shift+H | Horizontal line |
| Ctrl+Alt+D | Insert the <CODE> tag For HTML notes |
| Ctrl+Alt+Q | Insert the <BLOCKQUOTE> tag For HTML notes |
| Ctrl+Shift+Up | Move note up |
| Ctrl+Shift+Down | Move note down |
| Ctrl+T | Add tab |
| Ctrl+W | Close tab |